Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OTPOrthopedia homeobox. (325 aa)    
Predicted Functional Partners:
ALX3
ALX homeobox 3.
   
  
 0.930
RAX2
Retina and anterior neural fold homeobox protein 2 isoform 2.
   
    0.926
ARX
Aristaless related homeobox.
   
  
 0.905
DRGX
Dorsal root ganglia homeobox.
   
  
 0.893
ALX4
ALX homeobox 4.
   
    0.889
UNCX
UNC homeobox.
   
  
 0.886
SIM1
SIM bHLH transcription factor 1.
   
 
 0.651
OXT
Oxytocin-neurophysin 1; Neurophysin 1 specifically binds oxytocin.
      
 0.638
FOXG1
Forkhead box G1.
   
 
 0.594
PAX2
Paired box 2.
    
 
 0.536
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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