Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SERINC5Serine incorporator 5. (631 aa)    
Predicted Functional Partners:
SERINC3
Serine incorporator 3.
  
 
0.936
MFSD10
Major facilitator superfamily domain-containing protein 10.
      
 0.761
SERINC1
Serine incorporator 1.
  
 
0.756
SAMHD1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1.
      
 0.735
ICE2
Interactor of little elongation complex ELL subunit 2.
      
 0.702
TRAF6
TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...]
    
 
 0.699
F8S329_PIG
Env protein.
      
 0.640
NSMAF
Neutral sphingomyelinase activation associated factor.
      
 0.590
DCAF1
DDB1 and CUL4 associated factor 1.
      
 0.579
APOBEC3B
Uncharacterized protein.
      
 0.570
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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