STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LECT2Leukocyte cell derived chemotaxin 2. (201 aa)    
Predicted Functional Partners:
PLG
Plasmin heavy chain A, short form; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invas [...]
   
    0.943
SLCO1B3
Solute carrier organic anion transporter family member.
   
    0.938
SERPINA7
Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family.
   
    0.936
CHIA
Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family.
   
    0.814
CDC37L1
Cell division cycle 37 like 1.
      
 0.682
HRG
Uncharacterized protein.
   
  
 0.634
FABP1
Fatty acid-binding protein, liver; Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
   
  
 0.594
C4BPB
Complement component 4 binding protein beta.
   
    0.585
TIE1
Tyrosine kinase with immunoglobulin like and EGF like domains 1.
      
 0.582
TXNDC15
Thioredoxin domain-containing protein.
      
 0.572
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.