APBB3 protein (Sus scrofa) - STRING interaction network

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Score

APBB3

Amyloid beta precursor protein binding family B member 3. (492 aa)

Predicted Functional Partners:

APP

0.722

AP4M1

0.561

AP4E1

0.519

SCPEP1

0.518

NUCKS1

0.518

AHNAK2

0.516

SFXN3

0.515

LPAR5

0.511

SPPL2A

0.509

BACH1

0.509

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHNAK2	APBB3	ENSSSCP00000036365	ENSSSCP00000015282	PDZ domain-containing protein.	Amyloid beta precursor protein binding family B member 3.	0.516
AP4E1	AP4M1	ENSSSCP00000025160	ENSSSCP00000062848	Adaptor related protein complex 4 subunit epsilon 1.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	0.995
AP4E1	APBB3	ENSSSCP00000025160	ENSSSCP00000015282	Adaptor related protein complex 4 subunit epsilon 1.	Amyloid beta precursor protein binding family B member 3.	0.519
AP4E1	APP	ENSSSCP00000025160	ENSSSCP00000012805	Adaptor related protein complex 4 subunit epsilon 1.	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.529
AP4E1	SPPL2A	ENSSSCP00000025160	ENSSSCP00000004996	Adaptor related protein complex 4 subunit epsilon 1.	Signal peptide peptidase like 2A.	0.571
AP4M1	AP4E1	ENSSSCP00000062848	ENSSSCP00000025160	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	Adaptor related protein complex 4 subunit epsilon 1.	0.995
AP4M1	APBB3	ENSSSCP00000062848	ENSSSCP00000015282	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	Amyloid beta precursor protein binding family B member 3.	0.561
AP4M1	APP	ENSSSCP00000062848	ENSSSCP00000012805	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.753
AP4M1	SPPL2A	ENSSSCP00000062848	ENSSSCP00000004996	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	Signal peptide peptidase like 2A.	0.446
APBB3	AHNAK2	ENSSSCP00000015282	ENSSSCP00000036365	Amyloid beta precursor protein binding family B member 3.	PDZ domain-containing protein.	0.516
APBB3	AP4E1	ENSSSCP00000015282	ENSSSCP00000025160	Amyloid beta precursor protein binding family B member 3.	Adaptor related protein complex 4 subunit epsilon 1.	0.519
APBB3	AP4M1	ENSSSCP00000015282	ENSSSCP00000062848	Amyloid beta precursor protein binding family B member 3.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	0.561
APBB3	APP	ENSSSCP00000015282	ENSSSCP00000012805	Amyloid beta precursor protein binding family B member 3.	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.722
APBB3	BACH1	ENSSSCP00000015282	ENSSSCP00000057103	Amyloid beta precursor protein binding family B member 3.	Transcription regulator protein BACH1.	0.509
APBB3	LPAR5	ENSSSCP00000015282	ENSSSCP00000041164	Amyloid beta precursor protein binding family B member 3.	Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family.	0.511
APBB3	NUCKS1	ENSSSCP00000015282	ENSSSCP00000065252	Amyloid beta precursor protein binding family B member 3.	Nuclear casein kinase and cyclin dependent kinase substrate 1.	0.518
APBB3	SCPEP1	ENSSSCP00000015282	ENSSSCP00000033556	Amyloid beta precursor protein binding family B member 3.	Carboxypeptidase; Belongs to the peptidase S10 family.	0.518
APBB3	SFXN3	ENSSSCP00000015282	ENSSSCP00000043334	Amyloid beta precursor protein binding family B member 3.	Sidoreflexin.	0.515
APBB3	SPPL2A	ENSSSCP00000015282	ENSSSCP00000004996	Amyloid beta precursor protein binding family B member 3.	Signal peptide peptidase like 2A.	0.509
APP	AP4E1	ENSSSCP00000012805	ENSSSCP00000025160	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Adaptor related protein complex 4 subunit epsilon 1.	0.529