PDE6A protein (Sus scrofa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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co-expression

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gene fusions

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[Homology]

Score

PDE6A

Phosphodiesterase. (866 aa)

Predicted Functional Partners:

PDE6G

0.999

PDE6B

0.995

GNAT1

0.986

GNAT2

0.980

GNGT1

0.973

ADCY3

0.942

NT5E

0.940

ENPP3

0.939

ADCY5

0.934

GUK1

0.931

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY3	ADCY5	ENSSSCP00000058126	ENSSSCP00000020757	Adenylate cyclase 3.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.864
ADCY3	ENPP3	ENSSSCP00000058126	ENSSSCP00000029207	Adenylate cyclase 3.	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.	0.849
ADCY3	GNGT1	ENSSSCP00000058126	ENSSSCP00000016250	Adenylate cyclase 3.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.876
ADCY3	NT5E	ENSSSCP00000058126	ENSSSCP00000030955	Adenylate cyclase 3.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.555
ADCY3	PDE6A	ENSSSCP00000058126	ENSSSCP00000015367	Adenylate cyclase 3.	Phosphodiesterase.	0.942
ADCY3	PDE6B	ENSSSCP00000058126	ENSSSCP00000047634	Adenylate cyclase 3.	Phosphodiesterase.	0.933
ADCY3	PDE6G	ENSSSCP00000058126	ENSSSCP00000064660	Adenylate cyclase 3.	Uncharacterized protein.	0.868
ADCY5	ADCY3	ENSSSCP00000020757	ENSSSCP00000058126	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 3.	0.864
ADCY5	ENPP3	ENSSSCP00000020757	ENSSSCP00000029207	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.	0.934
ADCY5	GNAT1	ENSSSCP00000020757	ENSSSCP00000059180	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(T) subunit alpha-1 isoform X2.	0.473
ADCY5	GNGT1	ENSSSCP00000020757	ENSSSCP00000016250	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.928
ADCY5	NT5E	ENSSSCP00000020757	ENSSSCP00000030955	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.548
ADCY5	PDE6A	ENSSSCP00000020757	ENSSSCP00000015367	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.934
ADCY5	PDE6B	ENSSSCP00000020757	ENSSSCP00000047634	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.898
ADCY5	PDE6G	ENSSSCP00000020757	ENSSSCP00000064660	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.871
ENPP3	ADCY3	ENSSSCP00000029207	ENSSSCP00000058126	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.	Adenylate cyclase 3.	0.849
ENPP3	ADCY5	ENSSSCP00000029207	ENSSSCP00000020757	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.934
ENPP3	GUK1	ENSSSCP00000029207	ENSSSCP00000035398	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.	Guanylate kinase; Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP and indirectly, cyclic GMP (cGMP). Involved in the cGMP metabolism in photoreceptors.	0.920
ENPP3	NT5E	ENSSSCP00000029207	ENSSSCP00000030955	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.966
ENPP3	PDE6A	ENSSSCP00000029207	ENSSSCP00000015367	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.	Phosphodiesterase.	0.939