STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HBBHemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. (239 aa)    
Predicted Functional Partners:
LOC100737768
Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues.
  
0.999
HBQ1
Hemoglobin subunit theta-1; Belongs to the globin family.
  
0.942
HP
Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...]
   
 
 0.933
HBZ
Hemoglobin subunit zeta; The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin; Belongs to the globin family.
  
0.895
HBM
Hemoglobin subunit mu; Belongs to the globin family.
  
0.891
AHSP
Alpha-hemoglobin-stabilizing protein.
   
 
 0.687
MASP1
Mannan-binding lectin serine protease 1 isoform 2; Belongs to the peptidase S1 family.
   
 
 0.648
HBE1
Hemoglobin subunit epsilon; Hemoglobin epsilon chain is a beta-type chain found in early embryos; Belongs to the globin family.
  
0.600
NAPSA
Napsin A aspartic peptidase; Belongs to the peptidase A1 family.
    
 
 0.597
LOC100515788
GLOBIN domain-containing protein; Belongs to the globin family.
  
0.593
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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