STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEUP1Deuterosome assembly protein 1. (608 aa)    
Predicted Functional Partners:
PLK4
Polo like kinase 4.
    
 
 0.834
LOC100622849
Centrin-2.
      
 0.819
CCNO
Cyclin-O; Belongs to the cyclin family.
    
 
 0.754
FOXJ1
Forkhead box J1.
    
 
 0.707
STIL
STIL centriolar assembly protein.
      
 0.705
CEP78
Centrosomal protein 78.
      
 0.690
SASS6
Spindle assembly abnormal protein 6 homolog isoform X1.
    
 
 0.664
KRT4
Keratin 4; Belongs to the intermediate filament family.
      
 0.662
CDC20B
Cell division cycle 20B.
      
 0.653
MCIDAS
Multicilin; Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1.
      
 0.621
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.