Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DDI1DNA damage inducible 1 homolog 1. (379 aa)    
Predicted Functional Partners:
PSMD14
26S proteasome non-ATPase regulatory subunit 14.
   
 
 0.718
PSMD4
Proteasome 26S subunit, non-ATPase 4.
   
 
 0.700
ECE2
Uncharacterized protein.
   
 
 0.671
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
   
 
 0.645
RAD23A
RAD23 homolog A, nucleotide excision repair protein.
   
 
 0.645
UBB
Ubiquitin B.
   
 
 0.550
UBC
Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...]
   
 
 0.550
PSMA2
Proteasome endopeptidase complex.
   
 
 0.495
MPND
MPN domain-containing protein isoform 3.
   
 
 0.486
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 
 0.486
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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