| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| A0A287BQ31_PIG | CD2 | ENSSSCP00000058284 | ENSSSCP00000030865 | Ig-like domain-containing protein. | T-cell surface antigen CD2 isoform 2. | 0.408 |
| A0A287BQ31_PIG | CD247 | ENSSSCP00000058284 | ENSSSCP00000030740 | Ig-like domain-containing protein. | T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...] | 0.961 |
| A0A287BQ31_PIG | CD3D | ENSSSCP00000058284 | ENSSSCP00000028968 | Ig-like domain-containing protein. | T-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] | 0.976 |
| A0A287BQ31_PIG | CD3E | ENSSSCP00000058284 | ENSSSCP00000016015 | Ig-like domain-containing protein. | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | 0.988 |
| A0A287BQ31_PIG | CD3G | ENSSSCP00000058284 | ENSSSCP00000043282 | Ig-like domain-containing protein. | T-cell surface glycoprotein CD3 gamma chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] | 0.961 |
| A0A287BQ31_PIG | CD8A | ENSSSCP00000058284 | ENSSSCP00000040606 | Ig-like domain-containing protein. | CD8a molecule. | 0.534 |
| A0A287BQ31_PIG | CD8B | ENSSSCP00000058284 | ENSSSCP00000008768 | Ig-like domain-containing protein. | Ig-like domain-containing protein. | 0.599 |
| A0A287BQ31_PIG | SYK | ENSSSCP00000058284 | ENSSSCP00000033634 | Ig-like domain-containing protein. | 40 kDa tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the recepto [...] | 0.605 |
| A0A287BQ31_PIG | TRAT1 | ENSSSCP00000058284 | ENSSSCP00000024081 | Ig-like domain-containing protein. | T cell receptor associated transmembrane adaptor 1. | 0.568 |
| A0A287BQ31_PIG | ZAP70 | ENSSSCP00000058284 | ENSSSCP00000030533 | Ig-like domain-containing protein. | Tyrosine-protein kinase. | 0.672 |
| CD2 | A0A287BQ31_PIG | ENSSSCP00000030865 | ENSSSCP00000058284 | T-cell surface antigen CD2 isoform 2. | Ig-like domain-containing protein. | 0.408 |
| CD2 | CD247 | ENSSSCP00000030865 | ENSSSCP00000030740 | T-cell surface antigen CD2 isoform 2. | T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...] | 0.933 |
| CD2 | CD3D | ENSSSCP00000030865 | ENSSSCP00000028968 | T-cell surface antigen CD2 isoform 2. | T-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] | 0.946 |
| CD2 | CD3E | ENSSSCP00000030865 | ENSSSCP00000016015 | T-cell surface antigen CD2 isoform 2. | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | 0.950 |
| CD2 | CD3G | ENSSSCP00000030865 | ENSSSCP00000043282 | T-cell surface antigen CD2 isoform 2. | T-cell surface glycoprotein CD3 gamma chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] | 0.882 |
| CD2 | CD8A | ENSSSCP00000030865 | ENSSSCP00000040606 | T-cell surface antigen CD2 isoform 2. | CD8a molecule. | 0.947 |
| CD2 | CD8B | ENSSSCP00000030865 | ENSSSCP00000008768 | T-cell surface antigen CD2 isoform 2. | Ig-like domain-containing protein. | 0.496 |
| CD2 | TRAT1 | ENSSSCP00000030865 | ENSSSCP00000024081 | T-cell surface antigen CD2 isoform 2. | T cell receptor associated transmembrane adaptor 1. | 0.472 |
| CD2 | ZAP70 | ENSSSCP00000030865 | ENSSSCP00000030533 | T-cell surface antigen CD2 isoform 2. | Tyrosine-protein kinase. | 0.559 |
| CD247 | A0A287BQ31_PIG | ENSSSCP00000030740 | ENSSSCP00000058284 | T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...] | Ig-like domain-containing protein. | 0.961 |