Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
TNFSF18TNF superfamily member 18. (178 aa)    
Predicted Functional Partners:
TNFRSF18
TNFR-Cys domain-containing protein.
   
 0.981
CD40
Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).
   
 0.737
TNFSF4
Tumor necrosis factor ligand superfamily member 4 isoform X1; Belongs to the tumor necrosis factor family.
      
 0.726
LTBR
Uncharacterized protein.
   
 0.697
IL18BP
Interleukin 18 binding protein.
      
 0.614
ENOPH1
Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
      
 0.605
HAVCR1
Hepatitis A virus cellular receptor 1 isoform X1.
      
 0.555
TNFSF9
Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family.
      
 0.553
IDO1
Uncharacterized protein.
      
 0.544
IDO2
Indoleamine 2,3-dioxygenase 2.
      
 0.533
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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