PAPPA2 protein (Sus scrofa) - STRING interaction network

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Predicted Interactions

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Score

PAPPA2

Pappalysin 2. (1790 aa)

Predicted Functional Partners:

IGFBP5

0.685

RALGPS2

0.663

TVP23B

0.608

IGF1

0.579

ASTN1

0.553

ZNF777

0.548

ZFPM1

0.547

ESYT3

0.543

SLC34A1

0.542

BLOC1S4

0.531

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASTN1	PAPPA2	ENSSSCP00000063367	ENSSSCP00000016447	Astrotactin 1.	Pappalysin 2.	0.553
ASTN1	RALGPS2	ENSSSCP00000063367	ENSSSCP00000016457	Astrotactin 1.	Ras-specific guanine nucleotide-releasing factor RalGPS2 isoform X1.	0.858
BLOC1S4	ESYT3	ENSSSCP00000022070	ENSSSCP00000020398	Biogenesis of lysosomal organelles complex 1 subunit 4.	Extended synaptotagmin 3.	0.869
BLOC1S4	PAPPA2	ENSSSCP00000022070	ENSSSCP00000016447	Biogenesis of lysosomal organelles complex 1 subunit 4.	Pappalysin 2.	0.531
BLOC1S4	ZFPM1	ENSSSCP00000022070	ENSSSCP00000049549	Biogenesis of lysosomal organelles complex 1 subunit 4.	Zinc finger protein, FOG family member 1.	0.726
ESYT3	BLOC1S4	ENSSSCP00000020398	ENSSSCP00000022070	Extended synaptotagmin 3.	Biogenesis of lysosomal organelles complex 1 subunit 4.	0.869
ESYT3	PAPPA2	ENSSSCP00000020398	ENSSSCP00000016447	Extended synaptotagmin 3.	Pappalysin 2.	0.543
ESYT3	ZFPM1	ENSSSCP00000020398	ENSSSCP00000049549	Extended synaptotagmin 3.	Zinc finger protein, FOG family member 1.	0.730
IGF1	IGFBP5	ENSSSCP00000000915	ENSSSCP00000024248	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin-like growth factor-binding protein 5; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.	0.994
IGF1	PAPPA2	ENSSSCP00000000915	ENSSSCP00000016447	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Pappalysin 2.	0.579
IGFBP5	IGF1	ENSSSCP00000024248	ENSSSCP00000000915	Insulin-like growth factor-binding protein 5; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.994
IGFBP5	PAPPA2	ENSSSCP00000024248	ENSSSCP00000016447	Insulin-like growth factor-binding protein 5; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.	Pappalysin 2.	0.685
PAPPA2	ASTN1	ENSSSCP00000016447	ENSSSCP00000063367	Pappalysin 2.	Astrotactin 1.	0.553
PAPPA2	BLOC1S4	ENSSSCP00000016447	ENSSSCP00000022070	Pappalysin 2.	Biogenesis of lysosomal organelles complex 1 subunit 4.	0.531
PAPPA2	ESYT3	ENSSSCP00000016447	ENSSSCP00000020398	Pappalysin 2.	Extended synaptotagmin 3.	0.543
PAPPA2	IGF1	ENSSSCP00000016447	ENSSSCP00000000915	Pappalysin 2.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.579
PAPPA2	IGFBP5	ENSSSCP00000016447	ENSSSCP00000024248	Pappalysin 2.	Insulin-like growth factor-binding protein 5; IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.	0.685
PAPPA2	RALGPS2	ENSSSCP00000016447	ENSSSCP00000016457	Pappalysin 2.	Ras-specific guanine nucleotide-releasing factor RalGPS2 isoform X1.	0.663
PAPPA2	SLC34A1	ENSSSCP00000016447	ENSSSCP00000041097	Pappalysin 2.	Solute carrier family 34 member 1.	0.542
PAPPA2	TVP23B	ENSSSCP00000016447	ENSSSCP00000055971	Pappalysin 2.	Golgi apparatus membrane protein TVP23 homolog.	0.608