Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DTLDenticleless E3 ubiquitin protein ligase homolog. (729 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
    
 0.993
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.984
CDT1
PI-PLC Y-box domain-containing protein.
   
 
 0.979
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.942
WDHD1
WD repeat and HMG-box DNA binding protein 1.
   
  
 0.936
CDC45
Cell division cycle 45.
   
  
 0.915
EXO1
Exonuclease 1.
   
 
 0.912
MCM10
Minichromosome maintenance 10 replication initiation factor.
   
  
 0.906
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
  
 0.897
COPS5
COP9 signalosome subunit 5.
    
 0.894
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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