STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EN1Homeobox protein engrailed-like. (367 aa)    
Predicted Functional Partners:
FOXA2
Hepatocyte nuclear factor 3-beta isoform 1.
    
 
 0.797
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.633
WNT1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
  
 0.616
PAX2
Paired box 2.
   
  
 0.613
UNC79
Unc-79 homolog, NALCN channel complex subunit.
      
 0.611
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
  
 0.597
FOXG1
Forkhead box G1.
   
  
 0.595
NR4A2
Nuclear receptor subfamily 4 group A member 2 isoform X1.
      
 0.571
APCDD1L
APC down-regulated 1 like.
      
 0.554
DDC
Aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine; Belongs to the group II decarboxylase family.
      
 0.530
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.