ABCB11 protein (Sus scrofa) - STRING interaction network

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Score

ABCB11

ATP binding cassette subfamily B member 11. (1375 aa)

Predicted Functional Partners:

NR1H4

0.764

ATP8B1

0.762

CYP7A1

0.762

SLC10A1

0.731

MYO5B

0.721

NR0B2

0.712

SUOX

0.703

TJP2

0.671

SLCO1B3

0.647

NR1I2

0.638

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB11	ATP8B1	ENSSSCP00000016879	ENSSSCP00000005296	ATP binding cassette subfamily B member 11.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.762
ABCB11	CYP7A1	ENSSSCP00000016879	ENSSSCP00000033898	ATP binding cassette subfamily B member 11.	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...]	0.762
ABCB11	MYO5B	ENSSSCP00000016879	ENSSSCP00000071985	ATP binding cassette subfamily B member 11.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.721
ABCB11	NR0B2	ENSSSCP00000016879	ENSSSCP00000003868	ATP binding cassette subfamily B member 11.	Nuclear receptor subfamily 0 group B member 2.	0.712
ABCB11	NR1H4	ENSSSCP00000016879	ENSSSCP00000063172	ATP binding cassette subfamily B member 11.	Nuclear receptor subfamily 1 group H member 4.	0.764
ABCB11	NR1I2	ENSSSCP00000016879	ENSSSCP00000012669	ATP binding cassette subfamily B member 11.	Nuclear receptor subfamily 1 group I member 2.	0.638
ABCB11	SLC10A1	ENSSSCP00000016879	ENSSSCP00000002511	ATP binding cassette subfamily B member 11.	Solute carrier family 10 member 1.	0.731
ABCB11	SLCO1B3	ENSSSCP00000016879	ENSSSCP00000025888	ATP binding cassette subfamily B member 11.	Solute carrier organic anion transporter family member.	0.647
ABCB11	SUOX	ENSSSCP00000016879	ENSSSCP00000000396	ATP binding cassette subfamily B member 11.	Sulfite oxidase, mitochondrial isoform X1.	0.703
ABCB11	TJP2	ENSSSCP00000016879	ENSSSCP00000053359	ATP binding cassette subfamily B member 11.	Uncharacterized protein; Belongs to the MAGUK family.	0.671
ATP8B1	ABCB11	ENSSSCP00000005296	ENSSSCP00000016879	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	ATP binding cassette subfamily B member 11.	0.762
ATP8B1	MYO5B	ENSSSCP00000005296	ENSSSCP00000071985	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.542
ATP8B1	TJP2	ENSSSCP00000005296	ENSSSCP00000053359	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Uncharacterized protein; Belongs to the MAGUK family.	0.659
CYP7A1	ABCB11	ENSSSCP00000033898	ENSSSCP00000016879	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...]	ATP binding cassette subfamily B member 11.	0.762
CYP7A1	NR0B2	ENSSSCP00000033898	ENSSSCP00000003868	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...]	Nuclear receptor subfamily 0 group B member 2.	0.853
CYP7A1	NR1H4	ENSSSCP00000033898	ENSSSCP00000063172	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...]	Nuclear receptor subfamily 1 group H member 4.	0.846
CYP7A1	NR1I2	ENSSSCP00000033898	ENSSSCP00000012669	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...]	Nuclear receptor subfamily 1 group I member 2.	0.738
CYP7A1	SLC10A1	ENSSSCP00000033898	ENSSSCP00000002511	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...]	Solute carrier family 10 member 1.	0.642
CYP7A1	SLCO1B3	ENSSSCP00000033898	ENSSSCP00000025888	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...]	Solute carrier organic anion transporter family member.	0.583
MYO5B	ABCB11	ENSSSCP00000071985	ENSSSCP00000016879	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	ATP binding cassette subfamily B member 11.	0.721