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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL23Kelch like family member 23. (579 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 
 0.597
USP28
Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family.
    
 
 0.576
DCDC2B
Doublecortin domain containing 2B.
      
 0.527
UBR3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
      
 0.513
TRIM55
Tripartite motif containing 55.
    
 
 0.503
SNX16
Sorting nexin 16.
      
 0.489
DCDC2
Doublecortin domain containing 2.
      
 0.487
ZMYND11
Zinc finger MYND domain-containing protein 11 isoform X1.
      
 0.487
WWP1
E3 ubiquitin-protein ligase.
   
 
 0.484
LMO7
LIM domain 7.
    
 
 0.480
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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