node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACAA1 | ACAA2 | ENSSSCP00000011995 | ENSSSCP00000004865 | Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.931 |
ACAA1 | ACADL | ENSSSCP00000011995 | ENSSSCP00000017114 | Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Long-chain specific acyl-CoA dehydrogenase, mitochondrial; Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (By similarity). Among the different mitochondrial acyl-CoA dehydrogenas [...] | 0.981 |
ACAA1 | ACOX1 | ENSSSCP00000011995 | ENSSSCP00000034512 | Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.988 |
ACAA1 | ACOX3 | ENSSSCP00000011995 | ENSSSCP00000062930 | Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.971 |
ACAA1 | CPT2 | ENSSSCP00000011995 | ENSSSCP00000070352 | Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. | 0.677 |
ACAA1 | ECHS1 | ENSSSCP00000011995 | ENSSSCP00000040850 | Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.809 |
ACAA1 | ECI2 | ENSSSCP00000011995 | ENSSSCP00000001070 | Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA delta isomerase 2. | 0.980 |
ACAA1 | EHHADH | ENSSSCP00000011995 | ENSSSCP00000024105 | Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.991 |
ACAA1 | ETFA | ENSSSCP00000011995 | ENSSSCP00000034248 | Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Electron transfer flavoprotein subunit alpha. | 0.686 |
ACAA1 | HADHA | ENSSSCP00000011995 | ENSSSCP00000009137 | Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Trifunctional enzyme subunit alpha, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional en [...] | 0.991 |
ACAA2 | ACAA1 | ENSSSCP00000004865 | ENSSSCP00000011995 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.931 |
ACAA2 | ACADL | ENSSSCP00000004865 | ENSSSCP00000017114 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Long-chain specific acyl-CoA dehydrogenase, mitochondrial; Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (By similarity). Among the different mitochondrial acyl-CoA dehydrogenas [...] | 0.980 |
ACAA2 | ACOX1 | ENSSSCP00000004865 | ENSSSCP00000034512 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.972 |
ACAA2 | ACOX3 | ENSSSCP00000004865 | ENSSSCP00000062930 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.961 |
ACAA2 | CPT2 | ENSSSCP00000004865 | ENSSSCP00000070352 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. | 0.733 |
ACAA2 | ECHS1 | ENSSSCP00000004865 | ENSSSCP00000040850 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.817 |
ACAA2 | ECI2 | ENSSSCP00000004865 | ENSSSCP00000001070 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA delta isomerase 2. | 0.988 |
ACAA2 | EHHADH | ENSSSCP00000004865 | ENSSSCP00000024105 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.987 |
ACAA2 | ETFA | ENSSSCP00000004865 | ENSSSCP00000034248 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Electron transfer flavoprotein subunit alpha. | 0.810 |
ACAA2 | HADHA | ENSSSCP00000004865 | ENSSSCP00000009137 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Trifunctional enzyme subunit alpha, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional en [...] | 0.991 |