DOCK10 protein (Sus scrofa) - STRING interaction network

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Score

DOCK10

Dedicator of cytokinesis 10; Belongs to the DOCK family. (2201 aa)

Predicted Functional Partners:

CDC42

0.932

RAC2

0.792

RAC1

0.717

RAC3

0.707

HERC2

0.690

DOCK2

0.688

TOM1

0.611

DOCK8

0.589

DOCK5

0.519

DOCK1

0.519

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	DOCK1	ENSSSCP00000029815	ENSSSCP00000038012	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Dedicator of cytokinesis 1; Belongs to the DOCK family.	0.709
CDC42	DOCK10	ENSSSCP00000029815	ENSSSCP00000017201	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Dedicator of cytokinesis 10; Belongs to the DOCK family.	0.932
CDC42	DOCK2	ENSSSCP00000029815	ENSSSCP00000018020	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Dedicator of cytokinesis protein 2; Belongs to the DOCK family.	0.728
CDC42	DOCK5	ENSSSCP00000029815	ENSSSCP00000010303	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Dedicator of cytokinesis 5; Belongs to the DOCK family.	0.635
CDC42	DOCK8	ENSSSCP00000029815	ENSSSCP00000036299	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Dedicator of cytokinesis 8; Belongs to the DOCK family.	0.931
CDC42	RAC1	ENSSSCP00000029815	ENSSSCP00000062132	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Rac family small GTPase 1.	0.783
CDC42	RAC2	ENSSSCP00000029815	ENSSSCP00000070230	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Rac family small GTPase 2.	0.931
CDC42	RAC3	ENSSSCP00000029815	ENSSSCP00000047362	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Rac family small GTPase 3.	0.929
DOCK1	CDC42	ENSSSCP00000038012	ENSSSCP00000029815	Dedicator of cytokinesis 1; Belongs to the DOCK family.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.709
DOCK1	DOCK10	ENSSSCP00000038012	ENSSSCP00000017201	Dedicator of cytokinesis 1; Belongs to the DOCK family.	Dedicator of cytokinesis 10; Belongs to the DOCK family.	0.519
DOCK1	DOCK2	ENSSSCP00000038012	ENSSSCP00000018020	Dedicator of cytokinesis 1; Belongs to the DOCK family.	Dedicator of cytokinesis protein 2; Belongs to the DOCK family.	0.421
DOCK1	DOCK5	ENSSSCP00000038012	ENSSSCP00000010303	Dedicator of cytokinesis 1; Belongs to the DOCK family.	Dedicator of cytokinesis 5; Belongs to the DOCK family.	0.422
DOCK1	RAC1	ENSSSCP00000038012	ENSSSCP00000062132	Dedicator of cytokinesis 1; Belongs to the DOCK family.	Rac family small GTPase 1.	0.768
DOCK1	RAC2	ENSSSCP00000038012	ENSSSCP00000070230	Dedicator of cytokinesis 1; Belongs to the DOCK family.	Rac family small GTPase 2.	0.797
DOCK1	RAC3	ENSSSCP00000038012	ENSSSCP00000047362	Dedicator of cytokinesis 1; Belongs to the DOCK family.	Rac family small GTPase 3.	0.590
DOCK10	CDC42	ENSSSCP00000017201	ENSSSCP00000029815	Dedicator of cytokinesis 10; Belongs to the DOCK family.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.932
DOCK10	DOCK1	ENSSSCP00000017201	ENSSSCP00000038012	Dedicator of cytokinesis 10; Belongs to the DOCK family.	Dedicator of cytokinesis 1; Belongs to the DOCK family.	0.519
DOCK10	DOCK2	ENSSSCP00000017201	ENSSSCP00000018020	Dedicator of cytokinesis 10; Belongs to the DOCK family.	Dedicator of cytokinesis protein 2; Belongs to the DOCK family.	0.688
DOCK10	DOCK5	ENSSSCP00000017201	ENSSSCP00000010303	Dedicator of cytokinesis 10; Belongs to the DOCK family.	Dedicator of cytokinesis 5; Belongs to the DOCK family.	0.519
DOCK10	DOCK8	ENSSSCP00000017201	ENSSSCP00000036299	Dedicator of cytokinesis 10; Belongs to the DOCK family.	Dedicator of cytokinesis 8; Belongs to the DOCK family.	0.589