STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHRNGCholinergic receptor nicotinic gamma subunit. (519 aa)    
Predicted Functional Partners:
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
  
0.772
ECEL1
Endothelin-converting enzyme-like 1 isoform 1.
      
 0.608
SYTL1
Synaptotagmin like 1.
      
 0.604
THEMIS2
Thymocyte selection associated family member 2.
      
 0.603
MYOG
Myogenin; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast dif [...]
   
  
 0.596
MUSK
Muscle associated receptor tyrosine kinase.
   
 
 0.592
CHRNA2
Cholinergic receptor nicotinic alpha 2 subunit.
  
0.578
CHRNA7
Uncharacterized protein.
  
0.573
CHRNA4
Cholinergic receptor nicotinic alpha 4 subunit.
  
0.572
EIF4E2
Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.
      
 0.559
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.