STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCLYSelenocysteine lyase. (451 aa)    
Predicted Functional Partners:
ISCU
Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
 
 0.971
SEPHS1
Selenophosphate synthetase 1.
    
 0.971
A0A5G2RE08_PIG
NifU_N domain-containing protein.
  
 0.962
FXN
Frataxin.
   
 0.960
TXNRD2
Uncharacterized protein.
  
 0.937
TXNRD1
Thioredoxin reductase 1, cytoplasmic.
  
 0.936
NFU1
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform 2.
  
 0.933
TXNRD3
Thioredoxin reductase 3; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.925
MOCOS
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
    
 0.858
LYRM4
Uncharacterized protein; Belongs to the complex I LYR family.
   
 
 0.838
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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