GTPBP2 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

GTPBP2

GTP binding protein 2. (694 aa)

Predicted Functional Partners:

NPHP3

0.671

LAMC3

0.652

MRRF

0.644

ALDH4A1

0.644

AP4M1

0.604

PELO

0.600

REPS1

0.598

DCAF17

0.576

SNRNP70

0.569

MAP3K14

0.545

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH4A1	GTPBP2	ENSSSCP00000025588	ENSSSCP00000017322	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	GTP binding protein 2.	0.644
ALDH4A1	LAMC3	ENSSSCP00000025588	ENSSSCP00000006120	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Laminin subunit gamma 3.	0.609
ALDH4A1	NPHP3	ENSSSCP00000025588	ENSSSCP00000054748	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	TPR_REGION domain-containing protein.	0.645
AP4M1	DCAF17	ENSSSCP00000062848	ENSSSCP00000016900	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	DDB1 and CUL4 associated factor 17.	0.532
AP4M1	GTPBP2	ENSSSCP00000062848	ENSSSCP00000017322	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	GTP binding protein 2.	0.604
AP4M1	REPS1	ENSSSCP00000062848	ENSSSCP00000004479	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	RALBP1 associated Eps domain containing 1.	0.546
DCAF17	AP4M1	ENSSSCP00000016900	ENSSSCP00000062848	DDB1 and CUL4 associated factor 17.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	0.532
DCAF17	GTPBP2	ENSSSCP00000016900	ENSSSCP00000017322	DDB1 and CUL4 associated factor 17.	GTP binding protein 2.	0.576
DCAF17	REPS1	ENSSSCP00000016900	ENSSSCP00000004479	DDB1 and CUL4 associated factor 17.	RALBP1 associated Eps domain containing 1.	0.541
GTPBP2	ALDH4A1	ENSSSCP00000017322	ENSSSCP00000025588	GTP binding protein 2.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.644
GTPBP2	AP4M1	ENSSSCP00000017322	ENSSSCP00000062848	GTP binding protein 2.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	0.604
GTPBP2	DCAF17	ENSSSCP00000017322	ENSSSCP00000016900	GTP binding protein 2.	DDB1 and CUL4 associated factor 17.	0.576
GTPBP2	LAMC3	ENSSSCP00000017322	ENSSSCP00000006120	GTP binding protein 2.	Laminin subunit gamma 3.	0.652
GTPBP2	MAP3K14	ENSSSCP00000017322	ENSSSCP00000018362	GTP binding protein 2.	Mitogen-activated protein kinase kinase kinase 14.	0.545
GTPBP2	MRRF	ENSSSCP00000017322	ENSSSCP00000005928	GTP binding protein 2.	Ribosome-recycling factor, mitochondrial isoform 1.	0.644
GTPBP2	NPHP3	ENSSSCP00000017322	ENSSSCP00000054748	GTP binding protein 2.	TPR_REGION domain-containing protein.	0.671
GTPBP2	PELO	ENSSSCP00000017322	ENSSSCP00000017892	GTP binding protein 2.	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.	0.600
GTPBP2	REPS1	ENSSSCP00000017322	ENSSSCP00000004479	GTP binding protein 2.	RALBP1 associated Eps domain containing 1.	0.598
GTPBP2	SNRNP70	ENSSSCP00000017322	ENSSSCP00000043949	GTP binding protein 2.	Small nuclear ribonucleoprotein U1 subunit 70.	0.569
LAMC3	ALDH4A1	ENSSSCP00000006120	ENSSSCP00000025588	Laminin subunit gamma 3.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.609