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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAS2R41Taste receptor type 2. (307 aa)    
Predicted Functional Partners:
TAS1R2
Taste 1 receptor member 2.
     
 0.881
TAS1R1
Taste 1 receptor member 1.
     
 0.855
TAS1R3
G_PROTEIN_RECEP_F3_4 domain-containing protein.
     
 0.828
CASR
Extracellular calcium-sensing receptor; G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis. Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (By similarity). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. The G-protein- coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as [...]
     
 0.744
GPRC6A
G protein-coupled receptor class C group 6 member A.
      
 0.611
GRM4
Glutamate metabotropic receptor 4.
     
 0.597
TAS2R39
Taste 2 receptor member 39; Belongs to the G-protein coupled receptor T2R family.
  
  
0.550
FFAR4
Free fatty acid receptor 4 isoform GPR120-S.
      
 0.546
GNAT3
G protein subunit alpha transducin 3.
     
 0.545
GRM2
Glutamate metabotropic receptor 2.
     
 0.501
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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