STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAS2R60Taste receptor type 2. (314 aa)    
Predicted Functional Partners:
TAS1R2
Taste 1 receptor member 2.
     
 0.881
TAS1R1
Taste 1 receptor member 1.
     
 0.856
TAS1R3
G_PROTEIN_RECEP_F3_4 domain-containing protein.
     
 0.827
CASR
Extracellular calcium-sensing receptor; G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis. Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (By similarity). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. The G-protein- coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as [...]
     
 0.744
GPRC6A
G protein-coupled receptor class C group 6 member A.
      
 0.611
F1SSN1_PIG
Uncharacterized protein; Belongs to the G-protein coupled receptor T2R family.
   
   
0.576
FFAR4
Free fatty acid receptor 4 isoform GPR120-S.
      
 0.548
TAS2R39
Taste 2 receptor member 39; Belongs to the G-protein coupled receptor T2R family.
  
  
0.545
LOC100154902
Taste receptor type 2.
  
  
0.534
TAS2R4
Taste receptor type 2.
  
  
0.509
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.