PRSS2 protein (Sus scrofa) - STRING interaction network

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Score

PRSS2

Putative trypsinogen; Belongs to the peptidase S1 family. (247 aa)

Predicted Functional Partners:

LOC100302368

0.901

SPINK1

0.863

LOC100739735

0.850

LOC100621820

0.849

APP

0.840

ELANE

0.832

MMP8

0.808

LOC100520832

0.772

REG3G

0.772

MMP13

0.760

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	LOC100302368	ENSSSCP00000012805	ENSSSCP00000045861	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Trypsin.	0.840
APP	LOC100621820	ENSSSCP00000012805	ENSSSCP00000023533	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.838
APP	LOC100739735	ENSSSCP00000012805	ENSSSCP00000051113	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.838
APP	PRSS2	ENSSSCP00000012805	ENSSSCP00000017461	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Putative trypsinogen; Belongs to the peptidase S1 family.	0.840
ELANE	LOC100621820	ENSSSCP00000024494	ENSSSCP00000023533	Elastase, neutrophil expressed; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.459
ELANE	LOC100739735	ENSSSCP00000024494	ENSSSCP00000051113	Elastase, neutrophil expressed; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.446
ELANE	MMP8	ENSSSCP00000024494	ENSSSCP00000015908	Elastase, neutrophil expressed; Belongs to the peptidase S1 family.	Matrix metallopeptidase 8.	0.918
ELANE	PRSS2	ENSSSCP00000024494	ENSSSCP00000017461	Elastase, neutrophil expressed; Belongs to the peptidase S1 family.	Putative trypsinogen; Belongs to the peptidase S1 family.	0.832
LOC100302368	APP	ENSSSCP00000045861	ENSSSCP00000012805	Trypsin.	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.840
LOC100302368	LOC100621820	ENSSSCP00000045861	ENSSSCP00000023533	Trypsin.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.768
LOC100302368	LOC100739735	ENSSSCP00000045861	ENSSSCP00000051113	Trypsin.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.768
LOC100302368	PRSS2	ENSSSCP00000045861	ENSSSCP00000017461	Trypsin.	Putative trypsinogen; Belongs to the peptidase S1 family.	0.901
LOC100302368	SPINK1	ENSSSCP00000045861	ENSSSCP00000058066	Trypsin.	Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity).	0.917
LOC100520832	PRSS2	ENSSSCP00000008815	ENSSSCP00000017461	C-type lectin domain-containing protein.	Putative trypsinogen; Belongs to the peptidase S1 family.	0.772
LOC100520832	REG3G	ENSSSCP00000008815	ENSSSCP00000030478	C-type lectin domain-containing protein.	Lithostathine A chain; Might act as an inhibitor of spontaneous calcium carbonate precipitation.	0.802
LOC100621820	APP	ENSSSCP00000023533	ENSSSCP00000012805	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.838
LOC100621820	ELANE	ENSSSCP00000023533	ENSSSCP00000024494	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Elastase, neutrophil expressed; Belongs to the peptidase S1 family.	0.459
LOC100621820	LOC100302368	ENSSSCP00000023533	ENSSSCP00000045861	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Trypsin.	0.768
LOC100621820	LOC100739735	ENSSSCP00000023533	ENSSSCP00000051113	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.901
LOC100621820	PRSS2	ENSSSCP00000023533	ENSSSCP00000017461	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Putative trypsinogen; Belongs to the peptidase S1 family.	0.849