STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRBV19T cell receptor beta variable 19. (127 aa)    
Predicted Functional Partners:
EPHB6
EPH receptor B6.
    
 
 0.742
MAGEB3
Melanoma-associated antigen B3.
      
 0.665
CD3D
T-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...]
   
 
 0.551
MAGEB18
MAGE family member B18.
      
 0.516
MAGEB10-2
MAGE family member B10.
      
 0.516
RAD51AP1
RAD51 associated protein 1.
      
 0.503
TRAF3IP2
TRAF3 interacting protein 2.
    
 
 0.500
LOC102159844
MAGE domain-containing protein.
      
 0.477
LOC100154079
MAGE domain-containing protein.
      
 0.477
GZMK
Granzyme K; Belongs to the peptidase S1 family.
    
 
 0.468
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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