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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STRA8Stimulated by retinoic acid 8. (365 aa)    
Predicted Functional Partners:
REC8
Meiotic recombination protein REC8 homolog.
      
 0.900
DDX4
Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...]
   
  
 0.865
NANOS2
Nanos C2HC-type zinc finger 2; Belongs to the nanos family.
      
 0.864
DAZL
Deleted in azoospermia-like protein.
   
  
 0.861
SYCP3
Synaptonemal complex protein 3.
      
 0.860
SPO11
SPO11 meiotic protein covalently bound to DSB-like (S. cerevisiae).
      
 0.837
ZBTB16
Zinc finger and BTB domain containing 16.
      
 0.787
TNP1
Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
      
 0.772
SOHLH1
BHLH domain-containing protein.
      
 0.730
GFRA1
GDNF family receptor alpha 1.
      
 0.716
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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