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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSMEM1Serine rich single-pass membrane protein 1. (244 aa)    
Predicted Functional Partners:
SPACA1
Sperm acrosome membrane-associated protein 1; Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis. Important for male fertility.
      
 0.873
TSSK4
Testis-specific serine/threonine-protein kinase 4 isoform 1.
      
 0.788
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
      
 0.773
KSR2
Kinase suppressor of ras 2.
      
 0.765
CIB4
Calcium and integrin binding family member 4.
      
 0.751
SPATA46
Spermatogenesis associated 46.
      
 0.687
VPS54
Vacuolar protein sorting-associated protein 54 isoform 1.
      
 0.669
SPEF2
Sperm flagellar protein 2; Required for correct axoneme development in spermatozoa. Important for normal development of the manchette and sperm head morphology. Essential for male fertility. Plays a role in localization of the intraflagellar transport protein IFT20 to the manchette, suggesting function as an adapter for dynein- mediated protein transport during spermatogenesis. Also plays a role in bone growth where it seems to be required for normal osteoblast differentiation (By similarity).
      
 0.665
KLC3
Kinesin light chain 3.
      
 0.659
TMED4
Transmembrane p24 trafficking protein 4.
      
 0.656
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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