STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKP2S-phase kinase-associated protein 2 isoform 1. (436 aa)    
Predicted Functional Partners:
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.999
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.992
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
   
 0.990
CKS2
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.983
CDKN1B
p27Kip1.
    
 0.983
CCNA1
Cyclin-A1 isoform X1; Belongs to the cyclin family.
   
 0.981
CDKN1A
Cyclin dependent kinase inhibitor 1A.
    
 0.974
CDKN1C
Cyclin dependent kinase inhibitor 1C.
    
 0.974
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.971
CCNE2
G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family.
   
 0.957
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.