node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD34 | CD44 | ENSSSCP00000038479 | ENSSSCP00000014130 | CD34 molecule. | CD44 molecule (Indian blood group). | 0.946 |
CD34 | CDH5 | ENSSSCP00000038479 | ENSSSCP00000047033 | CD34 molecule. | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | 0.810 |
CD34 | CTNNB1 | ENSSSCP00000038479 | ENSSSCP00000031836 | CD34 molecule. | Catenin beta 1. | 0.529 |
CD34 | ENG | ENSSSCP00000038479 | ENSSSCP00000030121 | CD34 molecule. | Endoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells (By similarity). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a role in the binding of endothelial cells to int [...] | 0.938 |
CD34 | ITGB1 | ENSSSCP00000038479 | ENSSSCP00000030775 | CD34 molecule. | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.905 |
CD34 | KDR | ENSSSCP00000038479 | ENSSSCP00000029403 | CD34 molecule. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.866 |
CD34 | PECAM1 | ENSSSCP00000038479 | ENSSSCP00000044878 | CD34 molecule. | Platelet endothelial cell adhesion molecule; Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-692 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutr [...] | 0.945 |
CD34 | THY1 | ENSSSCP00000038479 | ENSSSCP00000050686 | CD34 molecule. | Thy-1 cell surface antigen. | 0.921 |
CD34 | VWF | ENSSSCP00000038479 | ENSSSCP00000000759 | CD34 molecule. | Von Willebrand factor; Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex, glycoprotein Ibalpha/IX/V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma (By similarity). | 0.926 |
CD44 | CD34 | ENSSSCP00000014130 | ENSSSCP00000038479 | CD44 molecule (Indian blood group). | CD34 molecule. | 0.946 |
CD44 | CDH5 | ENSSSCP00000014130 | ENSSSCP00000047033 | CD44 molecule (Indian blood group). | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | 0.587 |
CD44 | CTNNB1 | ENSSSCP00000014130 | ENSSSCP00000031836 | CD44 molecule (Indian blood group). | Catenin beta 1. | 0.621 |
CD44 | ENG | ENSSSCP00000014130 | ENSSSCP00000030121 | CD44 molecule (Indian blood group). | Endoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells (By similarity). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a role in the binding of endothelial cells to int [...] | 0.914 |
CD44 | ITGB1 | ENSSSCP00000014130 | ENSSSCP00000030775 | CD44 molecule (Indian blood group). | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.928 |
CD44 | PECAM1 | ENSSSCP00000014130 | ENSSSCP00000044878 | CD44 molecule (Indian blood group). | Platelet endothelial cell adhesion molecule; Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-692 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutr [...] | 0.888 |
CD44 | THY1 | ENSSSCP00000014130 | ENSSSCP00000050686 | CD44 molecule (Indian blood group). | Thy-1 cell surface antigen. | 0.920 |
CD44 | VWF | ENSSSCP00000014130 | ENSSSCP00000000759 | CD44 molecule (Indian blood group). | Von Willebrand factor; Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex, glycoprotein Ibalpha/IX/V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma (By similarity). | 0.575 |
CDH5 | CD34 | ENSSSCP00000047033 | ENSSSCP00000038479 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | CD34 molecule. | 0.810 |
CDH5 | CD44 | ENSSSCP00000047033 | ENSSSCP00000014130 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | CD44 molecule (Indian blood group). | 0.587 |
CDH5 | CTNNB1 | ENSSSCP00000047033 | ENSSSCP00000031836 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] | Catenin beta 1. | 0.998 |