Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IFNG | PSME1 | ENSSSCP00000036242 | ENSSSCP00000002192 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Proteasome activator complex subunit 1; Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity). | 0.942 |
| IFNG | PSME3 | ENSSSCP00000036242 | ENSSSCP00000071458 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] | 0.919 |
| NR1H3 | PSME3 | ENSSSCP00000014069 | ENSSSCP00000071458 | Nuclear receptor subfamily 1 group H member 3. | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] | 0.903 |
| NR1H3 | RXRA | ENSSSCP00000014069 | ENSSSCP00000070850 | Nuclear receptor subfamily 1 group H member 3. | Retinoid X receptor alpha. | 0.983 |
| PSMA3 | PSMA4 | ENSSSCP00000066263 | ENSSSCP00000065580 | Proteasome subunit alpha type. | Proteasome subunit alpha type. | 0.999 |
| PSMA3 | PSMA5 | ENSSSCP00000066263 | ENSSSCP00000007285 | Proteasome subunit alpha type. | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. | 0.998 |
| PSMA3 | PSMB2 | ENSSSCP00000066263 | ENSSSCP00000066215 | Proteasome subunit alpha type. | Proteasome subunit beta. | 0.998 |
| PSMA3 | PSMD11 | ENSSSCP00000066263 | ENSSSCP00000018786 | Proteasome subunit alpha type. | Proteasome 26S subunit, non-ATPase 11. | 0.993 |
| PSMA3 | PSMD14 | ENSSSCP00000066263 | ENSSSCP00000057773 | Proteasome subunit alpha type. | 26S proteasome non-ATPase regulatory subunit 14. | 0.996 |
| PSMA3 | PSME1 | ENSSSCP00000066263 | ENSSSCP00000002192 | Proteasome subunit alpha type. | Proteasome activator complex subunit 1; Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity). | 0.980 |
| PSMA3 | PSME3 | ENSSSCP00000066263 | ENSSSCP00000071458 | Proteasome subunit alpha type. | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] | 0.855 |
| PSMA4 | PSMA3 | ENSSSCP00000065580 | ENSSSCP00000066263 | Proteasome subunit alpha type. | Proteasome subunit alpha type. | 0.999 |
| PSMA4 | PSMA5 | ENSSSCP00000065580 | ENSSSCP00000007285 | Proteasome subunit alpha type. | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. | 0.999 |
| PSMA4 | PSMB2 | ENSSSCP00000065580 | ENSSSCP00000066215 | Proteasome subunit alpha type. | Proteasome subunit beta. | 0.999 |
| PSMA4 | PSMD11 | ENSSSCP00000065580 | ENSSSCP00000018786 | Proteasome subunit alpha type. | Proteasome 26S subunit, non-ATPase 11. | 0.994 |
| PSMA4 | PSMD14 | ENSSSCP00000065580 | ENSSSCP00000057773 | Proteasome subunit alpha type. | 26S proteasome non-ATPase regulatory subunit 14. | 0.997 |
| PSMA4 | PSME1 | ENSSSCP00000065580 | ENSSSCP00000002192 | Proteasome subunit alpha type. | Proteasome activator complex subunit 1; Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity). | 0.985 |
| PSMA4 | PSME3 | ENSSSCP00000065580 | ENSSSCP00000071458 | Proteasome subunit alpha type. | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] | 0.863 |
| PSMA5 | PSMA3 | ENSSSCP00000007285 | ENSSSCP00000066263 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. | Proteasome subunit alpha type. | 0.998 |
| PSMA5 | PSMA4 | ENSSSCP00000007285 | ENSSSCP00000065580 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. | Proteasome subunit alpha type. | 0.999 |
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