| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASNS | ASPA | ENSSSCP00000016267 | ENSSSCP00000041582 | Asparagine synthetase [glutamine-hydrolyzing]. | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | 0.904 |
| ASNS | ASS1 | ENSSSCP00000016267 | ENSSSCP00000040581 | Asparagine synthetase [glutamine-hydrolyzing]. | Argininosuccinate synthase 1. | 0.959 |
| ASNS | GOT1 | ENSSSCP00000016267 | ENSSSCP00000011226 | Asparagine synthetase [glutamine-hydrolyzing]. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.956 |
| ASNS | GOT2 | ENSSSCP00000016267 | ENSSSCP00000055842 | Asparagine synthetase [glutamine-hydrolyzing]. | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). | 0.969 |
| ASNS | IL4I1 | ENSSSCP00000016267 | ENSSSCP00000003464 | Asparagine synthetase [glutamine-hydrolyzing]. | Amine oxidase. | 0.905 |
| ASNS | LOC100525099 | ENSSSCP00000016267 | ENSSSCP00000036380 | Asparagine synthetase [glutamine-hydrolyzing]. | Amine oxidase. | 0.900 |
| ASNS | NAT8L | ENSSSCP00000016267 | ENSSSCP00000037500 | Asparagine synthetase [glutamine-hydrolyzing]. | N-acetyltransferase 8 like. | 0.920 |
| ASPA | ASNS | ENSSSCP00000041582 | ENSSSCP00000016267 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | Asparagine synthetase [glutamine-hydrolyzing]. | 0.904 |
| ASPA | ASS1 | ENSSSCP00000041582 | ENSSSCP00000040581 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | Argininosuccinate synthase 1. | 0.909 |
| ASPA | FOLH1B | ENSSSCP00000041582 | ENSSSCP00000053842 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | Glutamate carboxypeptidase 2; Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides (By similarity). In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N- aceylaspartylglutamate (NAAG), thereby releasing glutamate. Belongs to the peptidase M28 family. M28B subfamily. | 0.945 |
| ASPA | GOT1 | ENSSSCP00000041582 | ENSSSCP00000011226 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.913 |
| ASPA | GOT2 | ENSSSCP00000041582 | ENSSSCP00000055842 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). | 0.905 |
| ASPA | IL4I1 | ENSSSCP00000041582 | ENSSSCP00000003464 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | Amine oxidase. | 0.900 |
| ASPA | LOC100525099 | ENSSSCP00000041582 | ENSSSCP00000036380 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | Amine oxidase. | 0.902 |
| ASPA | NAT8L | ENSSSCP00000041582 | ENSSSCP00000037500 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | N-acetyltransferase 8 like. | 0.982 |
| ASPA | RIMKLA | ENSSSCP00000041582 | ENSSSCP00000004289 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | Ribosomal modification protein rimK like family member A. | 0.904 |
| ASPA | RIMKLB | ENSSSCP00000041582 | ENSSSCP00000058761 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | Ribosomal modification protein rimK like family member B. | 0.902 |
| ASS1 | ASNS | ENSSSCP00000040581 | ENSSSCP00000016267 | Argininosuccinate synthase 1. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.959 |
| ASS1 | ASPA | ENSSSCP00000040581 | ENSSSCP00000041582 | Argininosuccinate synthase 1. | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | 0.909 |
| ASS1 | GOT1 | ENSSSCP00000040581 | ENSSSCP00000011226 | Argininosuccinate synthase 1. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.939 |
STRING v12.5 is now available!
