STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCL2L11Uncharacterized protein. (433 aa)    
Predicted Functional Partners:
BCL2L1
Bcl-2-like protein 1; Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availab [...]
    
 0.988
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1.
    
 
 0.984
DYNLL1
Dynein light chain.
    
 0.976
BCL2A1
Bcl-2-related protein A1 isoform 1.
    
 
 0.909
BAK1
Uncharacterized protein.
    
 
 0.896
BCL2L10
Uncharacterized protein.
    
 
 0.872
BAD
BCL2 associated agonist of cell death.
    
 0.870
MAPK8
Mitogen-activated protein kinase.
    
 0.803
BCL2L14
BCL2 like 14.
    
 
 0.765
BOK
BCL2 family apoptosis regulator BOK.
    
 
 0.738
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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