STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3L6Y1_PIGWD_REPEATS_REGION domain-containing protein. (391 aa)    
Predicted Functional Partners:
TLE5
TLE family member 5, transcriptional modulator.
 
    
 0.810
NLRP5
Uncharacterized protein.
    
 
 0.664
OOEP
Oocyte-expressed protein homolog.
    
 
 0.606
NLRP7
NACHT domain-containing protein.
    
 
 0.589
PADI6
Protein-arginine deiminase type-6.
      
 0.589
NLRP9
NACHT, LRR and PYD domains-containing protein 9 isoform X1.
    
 
 0.584
PATL1
PAT1 homolog 1, processing body mRNA decay factor.
      
 0.573
ANKRD24
Ankyrin repeat domain 24.
      
 0.572
WEE2
Wee1-like protein kinase 2; Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation.
      
 0.571
EN1
Homeobox protein engrailed-like.
    
 
 0.499
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.