STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4orf46Chromosome 4 open reading frame 46. (112 aa)    
Predicted Functional Partners:
BHLHA9
Basic helix-loop-helix family member a9.
      
 0.876
RD3L
Retinal degeneration 3 like.
      
 0.876
GMPPA
Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose; Belongs to the transferase hexapeptide repeat family.
      
 0.610
ZPBP
Zona pellucida-binding protein 1; Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization. Belongs to the zona pellucida-binding protein Sp38 family.
      
 0.603
STK11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
   
  
 0.550
COX17
Cytochrome c oxidase copper chaperone; Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2).
      
 0.547
LBP
Uncharacterized protein.
      
 0.503
FGFR3
Fibroblast growth factor receptor.
   
  
 0.409
LHPP
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase.
      
 0.400
GALK1
Galactokinase 1.
      
 0.400
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.