STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAF1EAF domain-containing protein. (365 aa)    
Predicted Functional Partners:
ELL
Elongation factor for RNA polymerase II.
    
 0.955
AFF4
AF4/FMR2 family member 4 isoform X1.
    
 0.945
EAF2
ELL associated factor 2.
  
 
0.918
MLLT1
MLLT1 super elongation complex subunit.
   
 0.893
MLLT3
MLLT3 super elongation complex subunit.
   
 0.893
ELL2
Elongation factor for RNA polymerase II 2.
    
 0.878
ELL3
Elongation factor for RNA polymerase II 3.
    
 0.859
AFF1
AF4/FMR2 family member 1.
    
 0.858
TCEA1
Transcription elongation factor A1.
   
 0.857
POLR2I
DNA-directed RNA polymerase II subunit RPB9; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template (By similarity).
    
 0.852
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.