STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CORO6Coronin; Belongs to the WD repeat coronin family. (470 aa)    
Predicted Functional Partners:
ARHGEF5
Rho guanine nucleotide exchange factor 5.
      
 0.779
DUT
Deoxyuridine triphosphatase.
      0.679
IRGQ
Immunity related GTPase Q.
   
 
 0.615
RAPGEF1
Rap guanine nucleotide exchange factor 1.
   
 
 0.600
DHFR
Dihydrofolate reductase; Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2 (By similarity).
    
 0.586
ELMO2
Engulfment and cell motility 2.
   
  
 0.581
SORBS1
Sorbin and SH3 domain containing 1.
   
 
 0.559
KLHL35
Kelch like family member 35.
   
  
 0.532
DOCK5
Dedicator of cytokinesis 5; Belongs to the DOCK family.
   
  
 0.520
TMEM212
Transmembrane protein 212.
    
 
 0.520
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.