| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACD | ACR | ENSSSCP00000048391 | ENSSSCP00000042835 | ACD shelterin complex subunit and telomerase recruitment factor. | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | 0.827 |
| ACR | ACD | ENSSSCP00000042835 | ENSSSCP00000048391 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | ACD shelterin complex subunit and telomerase recruitment factor. | 0.827 |
| ACR | ACRBP | ENSSSCP00000042835 | ENSSSCP00000000746 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | 0.784 |
| ACR | BOLL | ENSSSCP00000042835 | ENSSSCP00000073604 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Boule homolog, RNA binding protein. | 0.826 |
| ACR | CREM | ENSSSCP00000042835 | ENSSSCP00000011843 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | cAMP responsive element modulator. | 0.666 |
| ACR | CRISP1 | ENSSSCP00000042835 | ENSSSCP00000001895 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Cysteine rich secretory protein 1; Belongs to the CRISP family. | 0.695 |
| ACR | IZUMO1 | ENSSSCP00000042835 | ENSSSCP00000057796 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Izumo sperm-egg fusion 1. | 0.746 |
| ACR | TESMIN | ENSSSCP00000042835 | ENSSSCP00000061454 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Testis expressed metallothionein like protein. | 0.750 |
| ACR | TNP1 | ENSSSCP00000042835 | ENSSSCP00000017139 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.824 |
| ACR | ZAN | ENSSSCP00000042835 | ENSSSCP00000067423 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Zonadhesin; Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling. | 0.788 |
| ACR | ZP3 | ENSSSCP00000042835 | ENSSSCP00000008213 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for zona matrix formation. May not have a sperm- binding activity by itself but may increase sperm-binding activity of ZPB. | 0.695 |
| ACRBP | ACR | ENSSSCP00000000746 | ENSSSCP00000042835 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | 0.784 |
| ACRBP | CRISP1 | ENSSSCP00000000746 | ENSSSCP00000001895 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Cysteine rich secretory protein 1; Belongs to the CRISP family. | 0.469 |
| ACRBP | IZUMO1 | ENSSSCP00000000746 | ENSSSCP00000057796 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Izumo sperm-egg fusion 1. | 0.402 |
| ACRBP | ZAN | ENSSSCP00000000746 | ENSSSCP00000067423 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Zonadhesin; Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling. | 0.620 |
| ACRBP | ZP3 | ENSSSCP00000000746 | ENSSSCP00000008213 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. | Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for zona matrix formation. May not have a sperm- binding activity by itself but may increase sperm-binding activity of ZPB. | 0.483 |
| BOLL | ACR | ENSSSCP00000073604 | ENSSSCP00000042835 | Boule homolog, RNA binding protein. | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | 0.826 |
| CREM | ACR | ENSSSCP00000011843 | ENSSSCP00000042835 | cAMP responsive element modulator. | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | 0.666 |
| CREM | TNP1 | ENSSSCP00000011843 | ENSSSCP00000017139 | cAMP responsive element modulator. | Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. | 0.503 |
| CRISP1 | ACR | ENSSSCP00000001895 | ENSSSCP00000042835 | Cysteine rich secretory protein 1; Belongs to the CRISP family. | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | 0.695 |