STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNASE2BDeoxyribonuclease 2 beta. (340 aa)    
Predicted Functional Partners:
DNASE1L1
Deoxyribonuclease-1-like 1.
      
 0.856
DNASE1L3
Deoxyribonuclease; Belongs to the DNase I family.
      
 0.782
DNASE1
Deoxyribonuclease-1; Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA (By similarity). Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity). Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs) (By similarity). NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (By s [...]
      
 0.704
FAM189A2
Family with sequence similarity 189 member A2.
      
 0.652
SOWAHA
Sosondowah ankyrin repeat domain family member A.
      
 0.651
GNS
N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
   
 
 0.528
BLK
Tyrosine-protein kinase.
      
 0.524
TXLNB
Taxilin beta.
      
 0.497
CELF1
CUGBP Elav-like family member 1.
      
 0.469
CORIN
Corin, serine peptidase.
      
 0.463
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.