STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCFC1R1Host cell factor C1 regulator 1 isoform 1. (138 aa)    
Predicted Functional Partners:
PRSS21
Serine protease 21; Belongs to the peptidase S1 family.
      
 0.764
FLYWCH2
FLYWCH family member 2.
      
 0.764
PRSS41
Serine protease 41; Belongs to the peptidase S1 family.
      
 0.764
PAQR4
Uncharacterized protein.
      
 0.764
KREMEN2
Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.
      
 0.730
THOC6
THO complex subunit 6 homolog isoform 1.
      
 0.724
BICDL2
BICD family like cargo adaptor 2.
      
 0.721
FLYWCH1
Uncharacterized protein.
      
 0.720
PRSS33
Serine protease 33; Belongs to the peptidase S1 family.
      
 0.690
E4F1
E4F transcription factor 1.
      
 0.674
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.