STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF183Ring finger protein 183. (245 aa)    
Predicted Functional Partners:
FATE1
Fetal and adult testis-expressed transcript protein homolog; Involved in the regulation of endoplasmic reticulum (ER)- mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling.
    
 
 0.654
RANBP3L
RAN binding protein 3 like.
      
 0.508
RNF186
Ring finger protein 186.
    
 
 0.507
BSPRY
B box and SPRY domain-containing protein isoform 2.
    
 
 0.504
C9orf43
Chromosome 9 open reading frame 43.
      
 0.503
RNF19A
E3 ubiquitin-protein ligase RNF19A; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR; Belongs to the RBR family. RNF19 subfamily.
   
 
 0.498
RNF181
RING-type domain-containing protein.
      
 0.487
NIF3L1
NGG1 interacting factor 3 like 1.
    
 
 0.483
ZNF165
Zinc finger protein 165 isoform X1.
   
 
 0.479
XBP1
BZIP domain-containing protein.
      
 0.478
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.