SLIRP protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRSF1	LRPPRC	ENSSSCP00000009540	ENSSSCP00000009020	G-rich RNA sequence binding factor 1.	Leucine-rich PPR motif-containing protein, mitochondrial.	0.679
GRSF1	SLIRP	ENSSSCP00000009540	ENSSSCP00000066201	G-rich RNA sequence binding factor 1.	RRM domain-containing protein.	0.714
LOC100512195	PIF1	ENSSSCP00000033116	ENSSSCP00000038141	PC4 domain-containing protein.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]	0.698
LOC100512195	SLIRP	ENSSSCP00000033116	ENSSSCP00000066201	PC4 domain-containing protein.	RRM domain-containing protein.	0.671
LRPPRC	GRSF1	ENSSSCP00000009020	ENSSSCP00000009540	Leucine-rich PPR motif-containing protein, mitochondrial.	G-rich RNA sequence binding factor 1.	0.679
LRPPRC	MRPS15	ENSSSCP00000009020	ENSSSCP00000057770	Leucine-rich PPR motif-containing protein, mitochondrial.	Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.	0.564
LRPPRC	PIF1	ENSSSCP00000009020	ENSSSCP00000038141	Leucine-rich PPR motif-containing protein, mitochondrial.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]	0.488
LRPPRC	PTCD3	ENSSSCP00000009020	ENSSSCP00000028455	Leucine-rich PPR motif-containing protein, mitochondrial.	Pentatricopeptide repeat domain 3.	0.886
LRPPRC	SLIRP	ENSSSCP00000009020	ENSSSCP00000066201	Leucine-rich PPR motif-containing protein, mitochondrial.	RRM domain-containing protein.	0.955
MRPS15	LRPPRC	ENSSSCP00000057770	ENSSSCP00000009020	Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.	Leucine-rich PPR motif-containing protein, mitochondrial.	0.564
MRPS15	PTCD3	ENSSSCP00000057770	ENSSSCP00000028455	Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.	Pentatricopeptide repeat domain 3.	0.963
MRPS15	SLIRP	ENSSSCP00000057770	ENSSSCP00000066201	Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family.	RRM domain-containing protein.	0.678
NDUFB4	NDUFS5	ENSSSCP00000058556	ENSSSCP00000003958	NADH:ubiquinone oxidoreductase subunit B4.	Uncharacterized protein.	0.999
NDUFB4	SLIRP	ENSSSCP00000058556	ENSSSCP00000066201	NADH:ubiquinone oxidoreductase subunit B4.	RRM domain-containing protein.	0.745
NDUFB4	TOMM7	ENSSSCP00000058556	ENSSSCP00000016311	NADH:ubiquinone oxidoreductase subunit B4.	Mitochondrial import receptor subunit TOM7 homolog; Required for assembly and stability of the TOM complex (By similarity). Positive regulator of PRKN translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria (By similarity).	0.585
NDUFS5	NDUFB4	ENSSSCP00000003958	ENSSSCP00000058556	Uncharacterized protein.	NADH:ubiquinone oxidoreductase subunit B4.	0.999
NDUFS5	SLIRP	ENSSSCP00000003958	ENSSSCP00000066201	Uncharacterized protein.	RRM domain-containing protein.	0.679
NDUFS5	TOMM7	ENSSSCP00000003958	ENSSSCP00000016311	Uncharacterized protein.	Mitochondrial import receptor subunit TOM7 homolog; Required for assembly and stability of the TOM complex (By similarity). Positive regulator of PRKN translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria (By similarity).	0.590
PIF1	LOC100512195	ENSSSCP00000038141	ENSSSCP00000033116	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]	PC4 domain-containing protein.	0.698
PIF1	LRPPRC	ENSSSCP00000038141	ENSSSCP00000009020	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]	Leucine-rich PPR motif-containing protein, mitochondrial.	0.488