STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C6orf120Chromosome 6 open reading frame 120. (184 aa)    
Predicted Functional Partners:
TMUB1
Ubiquitin-like domain-containing protein.
      
 0.752
TMEM259
Transmembrane protein 259.
      
 0.685
RNF170
E3 ubiquitin-protein ligase RNF170 isoform X1.
      
 0.679
ERLIN2
ER lipid raft associated 2.
    
 
 0.651
TMCO1
Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis. In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store. Belongs to the TMCO1 family.
      
 0.649
TMBIM6
Bax inhibitor 1; Suppressor of apoptosis. Modulates unfolded protein response signaling. Modulates ER calcium homeostasis by acting as a calcium-leak channel. Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation; Belongs to the BI1 family.
      
 0.628
RNF5
E3 ubiquitin-protein ligase RNF5.
      
 0.576
UBAC2
UBA domain containing 2.
      
 0.513
HERPUD2
HERPUD family member 2.
      
 0.502
FAM8A1
Family with sequence similarity 8 member A1.
      
 0.497
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.