node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADCY5 | GNAO1 | ENSSSCP00000020757 | ENSSSCP00000040441 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | 0.923 |
ADCY5 | GNAS-2 | ENSSSCP00000020757 | ENSSSCP00000029022 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Guanine nucleotide-binding protein G(s) subunit alpha. | 0.903 |
ADCY5 | GNG8 | ENSSSCP00000020757 | ENSSSCP00000025202 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.908 |
ADCYAP1R1 | GNAS-2 | ENSSSCP00000043415 | ENSSSCP00000029022 | Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family. | Guanine nucleotide-binding protein G(s) subunit alpha. | 0.908 |
ADCYAP1R1 | GNG8 | ENSSSCP00000043415 | ENSSSCP00000025202 | Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.918 |
APLNR | GNAO1 | ENSSSCP00000040764 | ENSSSCP00000040441 | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | 0.497 |
APLNR | GNG8 | ENSSSCP00000040764 | ENSSSCP00000025202 | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.907 |
APLNR | OPRM1 | ENSSSCP00000040764 | ENSSSCP00000004401 | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] | 0.499 |
DRD3 | GNAO1 | ENSSSCP00000012691 | ENSSSCP00000040441 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | 0.955 |
DRD3 | GNG8 | ENSSSCP00000012691 | ENSSSCP00000025202 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.907 |
GNAO1 | ADCY5 | ENSSSCP00000040441 | ENSSSCP00000020757 | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | 0.923 |
GNAO1 | APLNR | ENSSSCP00000040441 | ENSSSCP00000040764 | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. | 0.497 |
GNAO1 | DRD3 | ENSSSCP00000040441 | ENSSSCP00000012691 | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. | 0.955 |
GNAO1 | GNG8 | ENSSSCP00000040441 | ENSSSCP00000025202 | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.953 |
GNAO1 | KCNJ6 | ENSSSCP00000040441 | ENSSSCP00000057704 | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | Potassium voltage-gated channel subfamily J member 6. | 0.911 |
GNAO1 | LOC100154782 | ENSSSCP00000040441 | ENSSSCP00000016653 | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.932 |
GNAO1 | OPRM1 | ENSSSCP00000040441 | ENSSSCP00000004401 | Guanine nucleotide-binding protein G(O) subunit alpha isoform b. | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] | 0.933 |
GNAS-2 | ADCY5 | ENSSSCP00000029022 | ENSSSCP00000020757 | Guanine nucleotide-binding protein G(s) subunit alpha. | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | 0.903 |
GNAS-2 | ADCYAP1R1 | ENSSSCP00000029022 | ENSSSCP00000043415 | Guanine nucleotide-binding protein G(s) subunit alpha. | Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family. | 0.908 |
GNAS-2 | GNG8 | ENSSSCP00000029022 | ENSSSCP00000025202 | Guanine nucleotide-binding protein G(s) subunit alpha. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.911 |