STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLDIP2Polymerase delta-interacting protein 2 isoform 1. (368 aa)    
Predicted Functional Partners:
CYBA
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide; Belongs to the p22phox family.
   
  
 0.936
NOX3
NADPH oxidase 3.
      
 0.774
NOX4
NADPH oxidase 4.
      
 0.770
NOXA1
NADPH oxidase activator 1.
      
 0.665
NOX5
NADPH oxidase 5.
      
 0.650
A0A287AGI9_PIG
Skp1 domain-containing protein.
    
 
 0.575
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 
 0.575
UQCRC1
Ubiquinol-cytochrome c reductase core protein 1.
   
  
 0.575
NOX1
NADPH oxidase 1 isoform 1.
      
 0.574
NOXO1
NADPH oxidase organizer 1.
      
 0.572
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.