STRINGSTRING
NRIP1 protein (Sus scrofa) - STRING interaction network
"NRIP1" - Nuclear receptor interacting protein 1 in Sus scrofa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRIP1Nuclear receptor interacting protein 1 (1156 aa)    
Predicted Functional Partners:
ESRRG
Estrogen-related receptor gamma (396 aa)
       
 
  0.968
ESR1
Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA- binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (184 aa)
     
  0.959
PGR
Uncharacterized protein; Progesterone receptor (933 aa)
       
  0.951
EP300
E1A binding protein p300 (2421 aa)
     
  0.930
FOXA1
Forkhead box A1 (468 aa)
         
  0.912
TLE3
Transducin like enhancer of split 3 (779 aa)
         
  0.908
UBE2I
Uncharacterized protein; Ubiquitin-conjugating enzyme E2I; Belongs to the ubiquitin-conjugating enzyme family (158 aa)
         
  0.908
GATA3
GATA binding protein 3 (442 aa)
         
  0.906
SUMO1
Small ubiquitin-related modifier 1; Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instan [...] (101 aa)
         
  0.906
PIAS1
Protein inhibitor of activated STAT 1 (570 aa)
     
 
  0.903
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, Sus scrofa, pig, pigs, swine, wild boar
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