node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MYH7 | MYL1 | ENSSSCP00000070632 | ENSSSCP00000017116 | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Uncharacterized protein. | 0.991 |
MYH7 | MYL2 | ENSSSCP00000070632 | ENSSSCP00000034442 | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. | 0.997 |
MYH7 | MYOZ1 | ENSSSCP00000070632 | ENSSSCP00000010985 | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Myozenin-1; Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis (By similarity). | 0.736 |
MYH7 | TNNC2 | ENSSSCP00000070632 | ENSSSCP00000050173 | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. | 0.716 |
MYH7 | TNNI1 | ENSSSCP00000070632 | ENSSSCP00000031289 | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Troponin I1, slow skeletal type. | 0.902 |
MYH7 | TNNI2 | ENSSSCP00000070632 | ENSSSCP00000047863 | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Uncharacterized protein. | 0.793 |
MYH7 | TNNI3 | ENSSSCP00000070632 | ENSSSCP00000064102 | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Troponin I3, cardiac type. | 0.863 |
MYH7 | TNNT1 | ENSSSCP00000070632 | ENSSSCP00000069636 | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Troponin T, slow skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.919 |
MYH7 | TPM2 | ENSSSCP00000070632 | ENSSSCP00000041804 | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Uncharacterized protein; Belongs to the tropomyosin family. | 0.910 |
MYL1 | MYH7 | ENSSSCP00000017116 | ENSSSCP00000070632 | Uncharacterized protein. | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.991 |
MYL1 | MYL2 | ENSSSCP00000017116 | ENSSSCP00000034442 | Uncharacterized protein. | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. | 0.952 |
MYL1 | MYOZ1 | ENSSSCP00000017116 | ENSSSCP00000010985 | Uncharacterized protein. | Myozenin-1; Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis (By similarity). | 0.726 |
MYL1 | TNNC1 | ENSSSCP00000017116 | ENSSSCP00000043815 | Uncharacterized protein. | Troponin C, slow skeletal and cardiac muscles; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. | 0.709 |
MYL1 | TNNC2 | ENSSSCP00000017116 | ENSSSCP00000050173 | Uncharacterized protein. | Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. | 0.913 |
MYL1 | TNNI1 | ENSSSCP00000017116 | ENSSSCP00000031289 | Uncharacterized protein. | Troponin I1, slow skeletal type. | 0.944 |
MYL1 | TNNI2 | ENSSSCP00000017116 | ENSSSCP00000047863 | Uncharacterized protein. | Uncharacterized protein. | 0.951 |
MYL1 | TNNI3 | ENSSSCP00000017116 | ENSSSCP00000064102 | Uncharacterized protein. | Troponin I3, cardiac type. | 0.919 |
MYL1 | TNNT1 | ENSSSCP00000017116 | ENSSSCP00000069636 | Uncharacterized protein. | Troponin T, slow skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.936 |
MYL1 | TPM2 | ENSSSCP00000017116 | ENSSSCP00000041804 | Uncharacterized protein. | Uncharacterized protein; Belongs to the tropomyosin family. | 0.914 |
MYL2 | MYH7 | ENSSSCP00000034442 | ENSSSCP00000070632 | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.997 |