STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106504154Sex-determining region Y protein; Transcriptional regulator that controls a genetic switch in male development; Belongs to the SRY family. (236 aa)    
Predicted Functional Partners:
ZFY
Zinc finger X-chromosomal protein; Probable transcriptional activator; Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily.
   
 
 0.858
ZFX
Zinc finger X-chromosomal protein isoform 1.
   
 
 0.772
NANOG
Homeobox domain-containing protein.
    
 
 0.762
POU5F1
POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Belongs to the POU transcription factor family. Class-5 subfamily.
    
 
 0.748
RNASE1
Ribonuclease pancreatic; Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double- stranded RNA (By similarity); Belongs to the pancreatic ribonuclease family.
      
 0.658
LOC100624590
ATP-dependent RNA helicase DDX3X isoform 2; Belongs to the DEAD box helicase family.
    
 
 0.612
HOXC8
Homeobox C8.
   
 
 0.595
TBX4
Uncharacterized protein.
    
 
 0.594
A0A5G2QQY9_PIG
POU-specific domain-containing protein.
    
 
 0.583
RSPO1
R-spondin 1.
   
 
 0.578
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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