PTGIR protein (Sus scrofa) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

PTGIR

Prostaglandin I2 receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)

Predicted Functional Partners:

GNAS-2

0.906

GNAS

0.696

GNG8

0.627

PTGIS

0.610

PTGES2

0.570

GNB2

0.562

GNB4

0.562

GNB3

0.561

GNB1

0.561

GNB5

0.560

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNAS	GNB1	ENSSSCP00000029311	ENSSSCP00000048402	Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.	G protein subunit beta 1.	0.832
GNAS	GNB2	ENSSSCP00000029311	ENSSSCP00000008190	Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.	G protein subunit beta 2.	0.860
GNAS	GNB3	ENSSSCP00000029311	ENSSSCP00000000727	Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1.	0.821
GNAS	GNB4	ENSSSCP00000029311	ENSSSCP00000036910	Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.	G protein subunit beta 4.	0.992
GNAS	GNB5	ENSSSCP00000029311	ENSSSCP00000031679	Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.	G protein subunit beta 5.	0.805
GNAS	GNG8	ENSSSCP00000029311	ENSSSCP00000025202	Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.770
GNAS	PTGIR	ENSSSCP00000029311	ENSSSCP00000027306	Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.	Prostaglandin I2 receptor; Belongs to the G-protein coupled receptor 1 family.	0.696
GNAS-2	GNB1	ENSSSCP00000029022	ENSSSCP00000048402	Guanine nucleotide-binding protein G(s) subunit alpha.	G protein subunit beta 1.	0.916
GNAS-2	GNB2	ENSSSCP00000029022	ENSSSCP00000008190	Guanine nucleotide-binding protein G(s) subunit alpha.	G protein subunit beta 2.	0.916
GNAS-2	GNB3	ENSSSCP00000029022	ENSSSCP00000000727	Guanine nucleotide-binding protein G(s) subunit alpha.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1.	0.916
GNAS-2	GNB4	ENSSSCP00000029022	ENSSSCP00000036910	Guanine nucleotide-binding protein G(s) subunit alpha.	G protein subunit beta 4.	0.916
GNAS-2	GNB5	ENSSSCP00000029022	ENSSSCP00000031679	Guanine nucleotide-binding protein G(s) subunit alpha.	G protein subunit beta 5.	0.916
GNAS-2	GNG8	ENSSSCP00000029022	ENSSSCP00000025202	Guanine nucleotide-binding protein G(s) subunit alpha.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.911
GNAS-2	PTGIR	ENSSSCP00000029022	ENSSSCP00000027306	Guanine nucleotide-binding protein G(s) subunit alpha.	Prostaglandin I2 receptor; Belongs to the G-protein coupled receptor 1 family.	0.906
GNB1	GNAS	ENSSSCP00000048402	ENSSSCP00000029311	G protein subunit beta 1.	Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.	0.832
GNB1	GNAS-2	ENSSSCP00000048402	ENSSSCP00000029022	G protein subunit beta 1.	Guanine nucleotide-binding protein G(s) subunit alpha.	0.916
GNB1	GNB2	ENSSSCP00000048402	ENSSSCP00000008190	G protein subunit beta 1.	G protein subunit beta 2.	0.548
GNB1	GNB3	ENSSSCP00000048402	ENSSSCP00000000727	G protein subunit beta 1.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1.	0.613
GNB1	GNB4	ENSSSCP00000048402	ENSSSCP00000036910	G protein subunit beta 1.	G protein subunit beta 4.	0.549
GNB1	GNB5	ENSSSCP00000048402	ENSSSCP00000031679	G protein subunit beta 1.	G protein subunit beta 5.	0.617