node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD10 | CD1.1 | ENSSSCP00000044340 | ENSSSCP00000027437 | Ankyrin repeat domain 10. | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | 0.645 |
ANKRD10 | CDKL3 | ENSSSCP00000044340 | ENSSSCP00000015212 | Ankyrin repeat domain 10. | Cyclin dependent kinase like 3. | 0.787 |
B2M | CD1.1 | ENSSSCP00000050390 | ENSSSCP00000027437 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | 0.900 |
B2M | CD1E | ENSSSCP00000050390 | ENSSSCP00000066307 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | CD1e molecule. | 0.759 |
B2M | CD3E | ENSSSCP00000050390 | ENSSSCP00000016015 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | 0.754 |
B2M | CD4 | ENSSSCP00000050390 | ENSSSCP00000019155 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | CD4 molecule. | 0.560 |
B2M | CD80 | ENSSSCP00000050390 | ENSSSCP00000012679 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | CD80 molecule. | 0.526 |
B2M | IL4 | ENSSSCP00000050390 | ENSSSCP00000015193 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | 0.409 |
CD1.1 | ANKRD10 | ENSSSCP00000027437 | ENSSSCP00000044340 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | Ankyrin repeat domain 10. | 0.645 |
CD1.1 | B2M | ENSSSCP00000027437 | ENSSSCP00000050390 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | 0.900 |
CD1.1 | CD1E | ENSSSCP00000027437 | ENSSSCP00000066307 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | CD1e molecule. | 0.904 |
CD1.1 | CD3E | ENSSSCP00000027437 | ENSSSCP00000016015 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | 0.666 |
CD1.1 | CD4 | ENSSSCP00000027437 | ENSSSCP00000019155 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | CD4 molecule. | 0.663 |
CD1.1 | CD80 | ENSSSCP00000027437 | ENSSSCP00000012679 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | CD80 molecule. | 0.787 |
CD1.1 | CD83 | ENSSSCP00000027437 | ENSSSCP00000060788 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | Ig-like domain-containing protein. | 0.651 |
CD1.1 | CDKL3 | ENSSSCP00000027437 | ENSSSCP00000015212 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | Cyclin dependent kinase like 3. | 0.589 |
CD1.1 | IL4 | ENSSSCP00000027437 | ENSSSCP00000015193 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | 0.612 |
CD1.1 | RPA2 | ENSSSCP00000027437 | ENSSSCP00000072826 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | RPA_C domain-containing protein. | 0.590 |
CD1E | B2M | ENSSSCP00000066307 | ENSSSCP00000050390 | CD1e molecule. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | 0.759 |
CD1E | CD1.1 | ENSSSCP00000066307 | ENSSSCP00000027437 | CD1e molecule. | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | 0.904 |