| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| A0A287BQ31_PIG | B2M | ENSSSCP00000058284 | ENSSSCP00000050390 | Ig-like domain-containing protein. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | 0.500 |
| A0A287BQ31_PIG | CD1.1 | ENSSSCP00000058284 | ENSSSCP00000027437 | Ig-like domain-containing protein. | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | 0.638 |
| A0A287BQ31_PIG | CD1D | ENSSSCP00000058284 | ENSSSCP00000028542 | Ig-like domain-containing protein. | Ig-like domain-containing protein. | 0.638 |
| A0A287BQ31_PIG | CD4 | ENSSSCP00000058284 | ENSSSCP00000019155 | Ig-like domain-containing protein. | CD4 molecule. | 0.544 |
| B2M | A0A287BQ31_PIG | ENSSSCP00000050390 | ENSSSCP00000058284 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | Ig-like domain-containing protein. | 0.500 |
| B2M | CD1.1 | ENSSSCP00000050390 | ENSSSCP00000027437 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | 0.918 |
| B2M | CD1D | ENSSSCP00000050390 | ENSSSCP00000028542 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | Ig-like domain-containing protein. | 0.970 |
| B2M | CD4 | ENSSSCP00000050390 | ENSSSCP00000019155 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | CD4 molecule. | 0.533 |
| B2M | IL10 | ENSSSCP00000050390 | ENSSSCP00000016594 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.574 |
| CD1.1 | A0A287BQ31_PIG | ENSSSCP00000027437 | ENSSSCP00000058284 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | Ig-like domain-containing protein. | 0.638 |
| CD1.1 | B2M | ENSSSCP00000027437 | ENSSSCP00000050390 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | 0.918 |
| CD1.1 | CD1D | ENSSSCP00000027437 | ENSSSCP00000028542 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | Ig-like domain-containing protein. | 0.756 |
| CD1.1 | CD4 | ENSSSCP00000027437 | ENSSSCP00000019155 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | CD4 molecule. | 0.716 |
| CD1.1 | CD80 | ENSSSCP00000027437 | ENSSSCP00000012679 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | CD80 molecule. | 0.747 |
| CD1.1 | CD83 | ENSSSCP00000027437 | ENSSSCP00000060788 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | Ig-like domain-containing protein. | 0.675 |
| CD1.1 | CD86 | ENSSSCP00000027437 | ENSSSCP00000028828 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | T-lymphocyte activation antigen CD86 isoform 1. | 0.623 |
| CD1.1 | IL10 | ENSSSCP00000027437 | ENSSSCP00000016594 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.600 |
| CD1.1 | IL4 | ENSSSCP00000027437 | ENSSSCP00000015193 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] | 0.632 |
| CD1.1 | RPA2 | ENSSSCP00000027437 | ENSSSCP00000072826 | T-cell surface glycoprotein CD1a; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. | RPA_C domain-containing protein. | 0.656 |
| CD1D | A0A287BQ31_PIG | ENSSSCP00000028542 | ENSSSCP00000058284 | Ig-like domain-containing protein. | Ig-like domain-containing protein. | 0.638 |