PRKCZ protein (Sus scrofa) - STRING interaction network

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PRKCZ

Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa)

Predicted Functional Partners:

PARD6A

0.981

PARD6B

0.980

PARD6G

0.975

PARD3

0.975

LLGL2

0.967

CDC42

0.939

RAC2

0.936

PIAS4

0.934

PTEN

0.930

SUMO2

0.928

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	PARD3	ENSSSCP00000029815	ENSSSCP00000063272	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Par-3 family cell polarity regulator.	0.953
CDC42	PARD6A	ENSSSCP00000029815	ENSSSCP00000067234	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Par-6 family cell polarity regulator alpha.	0.981
CDC42	PARD6B	ENSSSCP00000029815	ENSSSCP00000036345	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Uncharacterized protein.	0.981
CDC42	PARD6G	ENSSSCP00000029815	ENSSSCP00000027155	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Par-6 family cell polarity regulator gamma.	0.981
CDC42	PRKCZ	ENSSSCP00000029815	ENSSSCP00000027683	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.939
CDC42	PTEN	ENSSSCP00000029815	ENSSSCP00000011128	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Uncharacterized protein.	0.953
CDC42	RAC2	ENSSSCP00000029815	ENSSSCP00000070230	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Rac family small GTPase 2.	0.931
LLGL2	PARD3	ENSSSCP00000049828	ENSSSCP00000063272	LLGL scribble cell polarity complex component 2.	Par-3 family cell polarity regulator.	0.554
LLGL2	PARD6A	ENSSSCP00000049828	ENSSSCP00000067234	LLGL scribble cell polarity complex component 2.	Par-6 family cell polarity regulator alpha.	0.646
LLGL2	PARD6B	ENSSSCP00000049828	ENSSSCP00000036345	LLGL scribble cell polarity complex component 2.	Uncharacterized protein.	0.785
LLGL2	PARD6G	ENSSSCP00000049828	ENSSSCP00000027155	LLGL scribble cell polarity complex component 2.	Par-6 family cell polarity regulator gamma.	0.687
LLGL2	PRKCZ	ENSSSCP00000049828	ENSSSCP00000027683	LLGL scribble cell polarity complex component 2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.967
PARD3	CDC42	ENSSSCP00000063272	ENSSSCP00000029815	Par-3 family cell polarity regulator.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.953
PARD3	LLGL2	ENSSSCP00000063272	ENSSSCP00000049828	Par-3 family cell polarity regulator.	LLGL scribble cell polarity complex component 2.	0.554
PARD3	PARD6A	ENSSSCP00000063272	ENSSSCP00000067234	Par-3 family cell polarity regulator.	Par-6 family cell polarity regulator alpha.	0.989
PARD3	PARD6B	ENSSSCP00000063272	ENSSSCP00000036345	Par-3 family cell polarity regulator.	Uncharacterized protein.	0.984
PARD3	PARD6G	ENSSSCP00000063272	ENSSSCP00000027155	Par-3 family cell polarity regulator.	Par-6 family cell polarity regulator gamma.	0.971
PARD3	PRKCZ	ENSSSCP00000063272	ENSSSCP00000027683	Par-3 family cell polarity regulator.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.975
PARD3	PTEN	ENSSSCP00000063272	ENSSSCP00000011128	Par-3 family cell polarity regulator.	Uncharacterized protein.	0.916
PARD3	RAC2	ENSSSCP00000063272	ENSSSCP00000070230	Par-3 family cell polarity regulator.	Rac family small GTPase 2.	0.915