STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
PLA2G1BPhospholipase A2, major isoenzyme; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. Belongs to the phospholipase A2 family. (146 aa)    
Predicted Functional Partners:
SPINK1
Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity).
   
  
 0.977
PLA2G3
Phospholipase A2 group III.
     
 0.975
PLA2G12B
Phospholipase A2 group XIIB.
   
 
 0.967
PLA2G5
Phospholipase A(2).
  
  
0.964
PLA2G2E
Phospholipase A(2).
  
  
0.963
PLA2G2F
Phospholipase A(2).
  
  
0.958
PLA2G2D
Phospholipase A(2).
  
  
0.958
PLA2G2C
PA2c domain-containing protein.
     
 0.954
PLA2G2A
Phospholipase A(2).
  
 
0.952
PLA2G7
Platelet-activating factor acetylhydrolase.
     
 0.947
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.